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The role of genetic variation of human metabolism for BMI, mental traits and mental disorders

Hebebrand, Johannes ; Peters, Triinu ; Schijven, Dick ; Hebebrand, Moritz ; Grasemann, Corinna ; Winkler, Thomas W. ; Heid, Iris M. ; Antel, Jochen ; Föcker, Manuel ; Tegeler, Lisa ; Brauner, Lena ; Adan, Roger A.H. ; Luykx, Jurjen J. ; Correll, Christoph U. ; König, Inke R. ; Hinney, Anke ; Libuda, Lars


Objective: The aim was to assess whether loci associated with metabolic traits also have a significant role in BMI and mental traits/disorders Methods: We first assessed the number of single nucleotide polymorphisms (SNPs) with genome-wide significance for human metabolism (NHGRI-EBI Catalog). These 516 SNPs (216 independent loci) were looked-up in genome-wide association studies for association ...


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