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Entwicklung neuer Antiostrogene vom Typ des 3,3'-Dihydroxy-alpha, beta-diathylstilbens und ihre Prufung am DMBA-induzierten, hormonabhangigen Mammacarcinom der SD-Ratte

Kranzfelder, G. ; Schneider, M. ; von Angerer, E. ; Schönenberger, H.


Development of new antiestrogens of the 3,3'-dihydroxy-alpha, beta-diethylstilbene-type and their evaluation on the DMBA-induced hormone dependent mammary carcinoma of the SD-rat (author's transl). The displacement of the phenolic OH-group of diethylstilbestrol into the 3,3'-position (trans-3,3'-dihydroxy-alpha, beta-diethylstilbene, compd. III) leads to a strong decrease of the estrogenic effect ...


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