Angerer, E. von, Prekajac, J., Schneider, M. R. and Berger, M. R. (1985) The inhibitory effect of 4-chloro-2-(2,6-dichloro-4-hydroxyphenyl)-1-ethyl-6-hydroxyindole (D 15413) on estrogen-dependent mammary tumors. Journal of cancer research and clinical oncology 110 (3), pp. 216-220.
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Abstract
The antineoplastic activity of 4-chloro-2-(2,6-dichloro-4-hydroxyphenyl)-1-ethyl-6-hydroxyindole (D 15413) was determined in several estrogen-dependent mammary tumor models. The growth of DMBA-induced rat mammary carcinomas was inhibited by doses ranging from 2 to 18 mg/kg. A dose of 6 X 12 mg/kg per week p.o. reduced the tumor area by 82% (control + 192%). D 15413 was also active against ...
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| Item type: | Article | ||||||||||||||||||||
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| Date: | 1985 | ||||||||||||||||||||
| Institutions: | Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer) | ||||||||||||||||||||
| Projects: | SFB 234 | ||||||||||||||||||||
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| Classification: |
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| Dewey Decimal Classification: | 500 Science > 570 Life sciences 500 Science > 540 Chemistry & allied sciences 600 Technology > 610 Medical sciences Medicine | ||||||||||||||||||||
| Status: | Published | ||||||||||||||||||||
| Refereed: | Yes, this version has been refereed | ||||||||||||||||||||
| Created at the University of Regensburg: | Yes | ||||||||||||||||||||
| Item ID: | 4729 |
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