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Prognostic Value of Molecular Breast Cancer Subtypes based on Her2, ESR1, PGR and Ki67 mRNA-Expression in Muscle Invasive Bladder Cancer

Kriegmair, M. C. ; Wirtz, R. M. ; Worst, T. S. ; Breyer, J. ; Ritter, M. ; Keck, B. ; Boehmer, C. ; Otto, W. ; Eckstein, M. ; Weis, C. A. ; Hartmann, A. ; Bolenz, C. ; Erben, P.


INTRODUCTION: Gene expression analyses have identified similarities between bladder and breast cancer, where clinical risk stratification is based on Her2, ESR1, PGR and Ki67 expression. The aim of the study was to assess the respective marker gene expression in patients treated with radical cystectomy for muscle-invasive bladder cancer (MIBC) and to evaluate the applicability of breast cancer ...


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