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Susceptibility of sodA- and sodB-deficientEscherichia colimutant towards antimicrobial photodynamic inactivationviathe type I-mechanism of action

Faraj Tabrizi, Pouriya ; Wennige, Sara ; Berneburg, Mark ; Maisch, Tim


Photodynamic antimicrobial chemotherapy (PACT) is a multi-target method to inactivate pathogenic microorganisms by exciting a photosensitizer (PS) with visible light of appropriate wavelength in the presence of molecular oxygen (O-3(2)). There are two major pathways by which reactive oxygen species (ROS) are produced. In type I (T-I)-reactions, radicals such as superoxide (O-2(center dot-)) and ...


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