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Evaluation of the antitumour activity of coumarin in prostate cancer models

Maucher, A. ; Kager, M. ; Angerer, E. von



Abstract

Responses to coumarin have been reported for patients suffering from malignant melanoma, metastatic renal carcinoma and, recently, advanced prostate cancer. These data together with some experimental evidence for antiprostatic effect prompted us to study the activity of coumarin in various prostate tumour models and evaluate the endocrine properties of this drug. In rats no antiandrogenic ...

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