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Alginate/Hydroxyapatite-Based Nanocomposite Scaffolds for Bone Tissue Engineering Improve Dental Pulp Biomineralization and Differentiation

Sancilio, Silvia ; Gallorini, Marialucia ; Di Nisio, Chiara ; Marsich, Eleonora ; Di Pietro, Roberta ; Schweikl, Helmut ; Cataldi, Amelia


Tissue engineering is widely recognized as a promising approach for bone repair and reconstruction. Several attempts have been made to achieve materials that must be compatible, osteoconductive, and osteointegrative and have mechanical strength to provide a structural support. Composite scaffolds consisting in biodegradable natural polymers are very promising constructs. Hydroxyapatite (HAp) can ...


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