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Vasopressor support vs. liberal fluid administration in deep inferior epigastric perforator (DIEP) free flap breast reconstruction – a randomized controlled trial

Anker, A. M. ; Prantl, L. ; Strauss, C. ; Brébant, V. ; Heine, N. ; Lamby, P. ; Geis, S. ; Schenkhoff, F. ; Pawlik, M. ; Klein, S. M.


BACKGROUND: Perioperatively, patients' hemodynamics are modulated predominantly by intravenous fluid administration and vasoactive pharmacological support. Vasopressor agents are suspected to be detrimental on free flap survival by the cause of vasoconstriction of the pedicle with consecutive reduced overall flap perfusion and by aggravation of flap dissection. OBJECTIVE: Anovel, standardized ...


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