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1-Benzyl-2-phenylindole- and 1,2-diphenylindole-based antiestrogens. Estimation of agonist and antagonist activities in transfection assays

Biberger, C. ; Angerer, E. von



Abstract

In the 2-phenylindole system, the side chain at the nitrogen atom dominates the endocrine profile both in respect to the reduction of estrogenic action and the increase of antiestrogenic potency. In previous papers we reported on 2-phenylindoles with aliphatic side chains and various functional groups [Biberger, C. and von Angerer, E., J. Steroid Biochem. Molec. Biol., 1996, 58, 31-43 and ...

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