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The fecal microbiome of ALS patients

Brenner, David ; Hiergeist, Andreas ; Adis, Carolin ; Mayer, Benjamin ; Gessner, André ; Ludolph, Albert C. ; Weishaupt, Jochen H.


Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative motor neuron disease accompanied by both systemic and central nervous system-specific inflammation as well as deregulated energy metabolism. These potential pathogenetic factors have recently been found to mutually interact with the gut microbiota, raising the hypothesis of a link between microbiome alterations and ALS pathogenesis. ...


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