Go to content
UR Home

Activation of soluble guanylyl cyclase signalling with cinaciguat improves impaired kidney function in diabetic mice

URN to cite this document:
DOI to cite this document:
Harloff, Manuela ; Prüschenk, Sally ; Seifert, Roland ; Schlossmann, Jens
Date of publication of this fulltext: 30 Aug 2021 10:34

This publication is part of the DEAL contract with Wiley.


Background and Purpose Diabetic nephropathy is the leading cause for end-stage renal disease worldwide. Until now, there is no specific therapy available. Standard treatment with inhibitors of the renin-angiotensin system just slows down progression. However, targeting the NO/sGC/cGMP pathway using sGC activators does prevent kidney damage. Thus, we investigated if the sGC activator cinaciguat ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons