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Lavage lipidomics signatures in children with cystic fibrosis and protracted bacterial bronchitis

Seidl, Elias ; Kiermeier, Hannah ; Liebisch, Gerhard ; Ballmann, Manfred ; Hesse, Sebastian ; Paul-Buck, Karl ; Ratjen, Felix ; Rietschel, Ernst ; Griese, Matthias



Abstract

Background: Balanced composition of a well-functioning pulmonary surfactant is crucial and essential for normal breathing. Here, we explored whether the composition of lipids recovered by broncho-alveolar lavage (BAL) in children with cystic fibrosis (CF) differ from children with protracted bacterial bronchitis (PBB) and controls. We wanted to differentiate, if alterations are primarily caused ...

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