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Establishment and Characterization of New Murine Breast Cancer Cell Lines

Bernhardt, Günther ; Beckenlehner, Karin ; Spruss, Thilo ; Schlemmer, Richard ; Reile, Herta ; Schönenberger, Helmut



Abstract

The establishment of two new breast cancer cell lines, MXT(+) and MXT(-), derived from the murine breast cancer models MXT-M-3, 2 MC (hormone-sensitive) and MXT-M-3, 2 (ovex) MC (hormone-insensitive), is described. Characterization of the cell lines was performed by investigation of morphology, steroid hormone receptor state, growth kinetics, and drug response as well as by cytogenetic analysis. ...

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