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Sodium‐chloride‐induced effects on the expression profile of human periodontal ligament fibroblasts with focus on simulated orthodontic tooth movement

Schröder, Agnes ; Nazet, Ute ; Neubert, Patrick ; Jantsch, Jonathan ; Spanier, Gerrit ; Proff, Peter ; Kirschneck, Christian


Increased salt (NaCl) consumption triggers chronic diseases such as hypertension or osteopenia. Its impact on orthodontic tooth movement and periodontitis, however, has not been investigated, although both processes are related to the immune system, with periodontal ligament fibroblasts (PDLFs) playing a key mediating role. Here, we investigated the impact of NaCl on the expression pattern of ...


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