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Development of a World Health Organization International Reference Panel for different genotypes of hepatitis E virus for nucleic acid amplification testing

Baylis, Sally A. ; Hanschmann, Kay-Martin O. ; Matsubayashi, Keiji ; Sakata, Hidekatsu ; Roque-Afonso, Anne-Marie ; Kaiser, Marco ; Corman, Victor M. ; Kamili, Saleem ; Aggarwal, Rakesh ; Trehanpati, Nirupma ; Gärtner, Thomas ; Thomson, Emma C. ; Davis, Christopher A. ; da Silva Filipe, Ana ; Abdelrahman, Tamer T. ; Blümel, Johannes ; Terao, Eriko ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ;



Zusammenfassung

Background: Globally, hepatitis E virus (HEV) is a major cause of acute viral hepatitis. Epidemiology and clinical presentation of hepatitis E vary greatly by location and are affected by the HEV genotype. Nucleic acid amplification technique (NAT)-based assays are important for the detection of acute HEV infection as well for monitoring chronic cases of hepatitis E. Objectives: The aim of the ...

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