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Loss of retinal ganglion cells in a new genetic mouse model for primary open‐angle glaucoma

Reinehr, Sabrina ; Koch, Dennis ; Weiss, Maximilian ; Froemel, Franziska ; Voss, Christina ; Dick, H. Burkhard ; Fuchshofer, Rudolf ; Joachim, Stephanie C.


Primary open-angle glaucoma (POAG) is one of the most common causes for blindness worldwide. Although an elevated intraocular pressure (IOP) is the main risk factor, the exact pathology remained indistinguishable. Therefore, it is necessary to have appropriate models to investigate these mechanisms. Here, we analysed a transgenic glaucoma mouse model (ss B1-CTGF) to elucidate new possible ...


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