Delacher, Michael ; Schmidl, Christian 
; Herzig, Yonatan ; Breloer, Minka ; Hartmann, Wiebke ; Brunk, Fabian ; Kägebein, Danny ; Träger, Ulrike ; Hofer, Ann-Cathrin ; Bittner, Sebastian ; Weichenhan, Dieter ; Imbusch, Charles D. ; Hotz-Wagenblatt, Agnes ; Hielscher, Thomas ; Breiling, Achim ; Federico, Giuseppina ; Gröne, Hermann-Josef ; Schmid, Roland M. ; Rehli, Michael ; Abramson, Jakub ; Feuerer, Markus
; Herzig, Yonatan ; Breloer, Minka ; Hartmann, Wiebke ; Brunk, Fabian ; Kägebein, Danny ; Träger, Ulrike ; Hofer, Ann-Cathrin ; Bittner, Sebastian ; Weichenhan, Dieter ; Imbusch, Charles D. ; Hotz-Wagenblatt, Agnes ; Hielscher, Thomas ; Breiling, Achim ; Federico, Giuseppina ; Gröne, Hermann-Josef ; Schmid, Roland M. ; Rehli, Michael ; Abramson, Jakub ; Feuerer, Markus 
Zusammenfassung
The transcriptional regulator Rbpj is involved in T-helper (T-H) subset polarization, but its function in T-reg cells remains unclear. Here we show that T-reg-specific Rbpj deletion leads to splenomegaly and lymphadenopathy despite increased numbers of T-reg cells with a polyclonal TCR repertoire. A specific defect of Rbpj-deficient T-reg cells in controlling T(H)2 polarization and B cell ...
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