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Identification of phase-II metabolites from human serum samples after oral intake of a willow bark extract

Untergehrer, Monika ; Kiermaier, Josef ; Reintjes, Susanne ; Heilmann, Jörg ; Jürgenliemk, Guido



Abstract

Background: Willow bark (Salicis cortex) is a herbal medicinal drug used to treat fever and pain, such as headaches and lower back pain. Until now, it has not been fully understood which compounds are responsible for the efficacy of the drug. Purpose: Although salicylic acid is known as a metabolite of salicylic alcohol derivatives of willow bark in vivo, it has been shown in previous studies ...

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