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The nuclear matrix protein Matr3 regulates processing of the synaptic microRNA-138-5p

Weiss, Kerstin ; Treiber, Thomas ; Meister, Gunter ; Schratt, Gerhard


microRNA-dependent post-transcriptional control represents an important gene-regulatory layer in post-mitotic neuronal development and synaptic plasticity. We recently identified the brain-enriched miR-138 as a negative regulator of dendritic spine morphogenesis in rat hippocampal neurons. A potential involvement of miR-138 in cognition is further supported by a recent GWAS study on memory ...


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