Go to content
UR Home

Similar Piperacillin/Tazobactam Target Attainment in Obese versus Nonobese Patients despite Differences in Interstitial Tissue Fluid Pharmacokinetics

URN to cite this document:
DOI to cite this document:
Busse, David ; Simon, Philipp ; Petroff, David ; Dorn, Christoph ; Schmitt, Lisa ; Bindellini, Davide ; Kratzer, Alexander ; Dietrich, Arne ; Zeitlinger, Markus ; Huisinga, Wilhelm ; Michelet, Robin ; Wrigge, Hermann ; Kloft, Charlotte
License: Creative Commons Attribution 4.0
PDF - Published Version
Date of publication of this fulltext: 04 Oct 2021 08:54


Precision dosing of piperacillin/tazobactam in obese patients is compromised by sparse information on target-site exposure. We aimed to evaluate the appropriateness of current and alternative piperacillin/tazobactam dosages in obese and nonobese patients. Based on a prospective, controlled clinical trial in 30 surgery patients (15 obese/15 nonobese; 0.5-h infusion of 4 g/0.5 g ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: daten@ur.de
0941 943 -5707

Contact persons