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U-DCS: characterization of the first permanent human dendritic sarcoma cell line

Mellert, Kevin ; Benckendorff, Julian ; Leithäuser, Frank ; Zimmermann, Katarzyna ; Wiegand, Peter ; Frascaroli, Giada ; Buck, Michaela ; Malaise, Muriel ; Hartmann, Gunther ; Barchet, Winfried ; Fürst, Daniel ; Mytilineos, Joannis ; Mayer-Steinacker, Regine ; Viardot, Andreas ; Möller, Peter


A dendritic cell sarcoma cell line, U-DCS, was established from a dendritic cell sarcoma in a 53-year-old Caucasian male patient. Since its establishment, U-DCS has maintained stable phenotypic characteristics in vitro and has a doubling time of approximately 2 days under standard culture conditions. U-DCS is growing with typical dendritic cell morphology in tissue and expresses the dendritic ...


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