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High Stroma T-Cell Infiltration is Associated with Better Survival in Stage pT1 Bladder Cancer

Hülsen, Sabine ; Lippolis, Eleonora ; Ferrazzi, Fulvia ; Otto, Wolfgang ; Distel, Luitpold ; Fietkau, Rainer ; Denzinger, Stefan ; Breyer, Johannes ; Burger, Maximilian ; Bertz, Simone ; Eckstein, Markus ; Ebner, Annette ; Hartmann, Arndt ; Geppert, Carol-I.


Stage pT1 bladder cancer (BC) shows highly diverse outcomes. Predictive markers are required to stratify patients for personalized treatment. The present study aimed to validate immune response quantification as a prognostic marker. Patients with pT1 BC (n = 167) treated by transurethral resection of the bladder (TURB) were enrolled. Formaldehyde-fixed paraffin-embedded material was stained for ...


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