Loescher, Christine M. ; Breitkreuz, Martin ; Li, Yong ; Nickel, Alexander ; Unger, Andreas ; Dietl, Alexander ; Schmidt, Andreas ; Mohamed, Belal A. 
; Kötter, Sebastian ; Schmitt, Joachim P. ; Krüger, Marcus ; Krüger, Martina ; Toischer, Karl ; Maack, Christoph ; Leichert, Lars I. ; Hamdani, Nazha ; Linke, Wolfgang A.
; Kötter, Sebastian ; Schmitt, Joachim P. ; Krüger, Marcus ; Krüger, Martina ; Toischer, Karl ; Maack, Christoph ; Leichert, Lars I. ; Hamdani, Nazha ; Linke, Wolfgang A. 
Zusammenfassung
The relationship between oxidative stress and cardiac stiffness is thought to involve modifications to the giant muscle protein titin, which in turn can determine the progression of heart disease. In vitro studies have shown that S-glutathionylation and disulfide bonding of titin fragments could alter the elastic properties of titin; however, whether and where titin becomes oxidized in vivo is ...
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