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Physical Activity Does Not Lower the Risk of Lung Cancer

Baumeister, Sebastian-Edgar ; Leitzmann, Michael F. ; Bahls, Martin ; Meisinger, Christa ; Amos, Christopher I. ; Hung, Rayjean J. ; Teumer, Alexander ; Baurecht, Hansjörg


Observational studies have suggested that physical activity might lower the risk of lung cancer in former and current smokers, but not in never-smokers. Using genetic instruments for self-reported and accelerometer-measured physical activity traits implemented through two-sample Mendelian randomization (MR), we sought to strengthen the evidence for causality. We used 18 genome-wide significant (P ...


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