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A gammaherpesvirus licenses CD8 T cells to protect the host from pneumovirus-induced immunopathologies

Dourcy, Mickaël ; Maquet, Céline ; Dams, Lorène ; Gilliaux, Gautier ; Javaux, Justine ; Desmecht, Daniel ; Mack, Matthias ; Dewals, Benjamin G. ; Machiels, Bénédicte ; Gillet, Laurent


Human respiratory syncytial virus (RSV) is a pneumovirus that causes severe infections in infants worldwide. Despite intensive research, safe and effective vaccines against RSV have remained elusive. The main reason is that RSV infection of children previously immunized with formalin-inactivated-RSV vaccines has been associated with exacerbated pathology, a phenomenon called RSV vaccine-enhanced ...


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