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Tumor Cell Invasion in Glioblastoma

Vollmann-Zwerenz, Arabel ; Leidgens, Verena ; Feliciello, Giancarlo ; Klein, Christoph A. ; Hau, Peter


Glioblastoma (GBM) is a particularly devastating tumor with a median survival of about 16 months. Recent research has revealed novel insights into the outstanding heterogeneity of this type of brain cancer. However, all GBM subtypes share the hallmark feature of aggressive invasion into the surrounding tissue. Invasive glioblastoma cells escape surgery and focal therapies and thus represent a ...


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