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Three-dimensional Monte Carlo-based voxel-wise tumor dosimetry in patients with neuroendocrine tumors who underwent 177Lu-DOTATOC therapy

Goetz, Th. I. ; Lang, E. W. ; Prante, O. ; Maier, A. ; Cordes, M. ; Kuwert, T. ; Ritt, P. ; Schmidkonz, Christian


Background Patients with advanced neuroendocrine tumors (NETs) of the midgut are suitable candidates for Lu-177-DOTATOC therapy. Integrated SPECT/CT systems have the potential to help improve the accuracy of patient-specific tumor dosimetry. Dose estimations to target organs are generally performed using the Medical Internal Radiation Dose scheme. We present a novel Monte Carlo-based voxel-wise ...


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