Abstract
Multiheteroatom-containing small-sized cyclic molecules such as 2-iminothiazolidines are often found to possess beneficial pharmacological properties. In this review article, the biological significance of 2-iminothiazolidines is discussed and the literature reports published in the last 15 years spanning from 2006 to 2020 describing various preparative routes to access 2-iminothiazolidine ...
Abstract
Multiheteroatom-containing small-sized cyclic molecules such as 2-iminothiazolidines are often found to possess beneficial pharmacological properties. In this review article, the biological significance of 2-iminothiazolidines is discussed and the literature reports published in the last 15 years spanning from 2006 to 2020 describing various preparative routes to access 2-iminothiazolidine derivatives have been categorically and chronologically described. The notable synthetic methods discussed here involve ring-expansion transformations of nonactivated and activated aziridines, thiiranes, epoxides, and other miscellaneous reactions.
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