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Cortical thickness and resting‐state cardiac function across the lifespan: A cross‐sectional pooled mega‐analysis

Koenig, Julian ; Abler, Birgit ; Agartz, Ingrid ; Åkerstedt, Torbjörn ; Andreassen, Ole A. ; Anthony, Mia ; Bär, Karl‐Jürgen ; Bertsch, Katja ; Brown, Rebecca C. ; Brunner, Romuald ; Carnevali, Luca ; Critchley, Hugo D. ; Cullen, Kathryn R. ; Geus, Eco J. C. ; Cruz, Feliberto ; Dziobek, Isabel ; Ferger, Marc D. ; Fischer, Håkan ; Flor, Herta ; Gaebler, Michael ; Gianaros, Peter J. ; Giummarra, Melita J. ; Greening, Steven G. ; Guendelman, Simon ; Heathers, James A. J. ; Herpertz, Sabine C. ; Hu, Mandy X. ; Jentschke, Sebastian ; Kaess, Michael ; Kaufmann, Tobias ; Klimes‐Dougan, Bonnie ; Koelsch, Stefan ; Krauch, Marlene ; Kumral, Deniz ; Lamers, Femke ; Lee, Tae‐Ho ; Lekander, Mats ; Lin, Feng ; Lotze, Martin ; Makovac, Elena ; Mancini, Matteo ; Mancke, Falk ; Månsson, Kristoffer N. T. ; Manuck, Stephen B. ; Mather, Mara ; Meeten, Frances ; Min, Jungwon ; Mueller, Bryon ; Muench, Vera ; Nees, Frauke ; Nga, Lin ; Nilsonne, Gustav ; Ordonez Acuna, Daniela ; Osnes, Berge ; Ottaviani, Cristina ; Penninx, Brenda W. J. H. ; Ponzio, Allison ; Poudel, Govinda R. ; Reinelt, Janis ; Ren, Ping ; Sakaki, Michiko ; Schumann, Andy ; Sørensen, Lin ; Specht, Karsten ; Straub, Joana ; Tamm, Sandra ; Thai, Michelle ; Thayer, Julian F. ; Ubani, Benjamin ; Mee, Denise J. ; Velzen, Laura S. ; Ventura‐Bort, Carlos ; Villringer, Arno ; Watson, David R. ; Wei, Luqing ; Wendt, Julia ; Schreiner, Melinda Westlund ; Westlye, Lars T. ; Weymar, Mathias ; Winkelmann, Tobias ; Wu, Guo‐Rong ; Yoo, Hyun Joo ; Quintana, Daniel S.



Abstract

Understanding the association between autonomic nervous system [ANS] function and brain morphology across the lifespan provides important insights into neurovisceral mechanisms underlying health and disease. Resting-state ANS activity, indexed by measures of heart rate [HR] and its variability [HRV] has been associated with brain morphology, particularly cortical thickness [CT]. While findings ...

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