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Underdiagnosed veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) as a major cause of multi-organ failure in acute leukemia transplant patients: an analysis from the EBMT Acute Leukemia Working Party

Bazarbachi, Abdul Hamid ; Al Hamed, Rama ; Labopin, Myriam ; Halaburda, Kazimierz ; Labussiere, Helene ; Bernasconi, Paolo ; Schroyens, Wilfried ; Gandemer, Virginie ; Schaap, Nicolaas P. M. ; Loschi, Michael ; Jindra, Pavel ; Snowden, John ; Wu, Depei ; Guffroy, Blandine ; Rovira, Montserrat ; Chantepie, Sylvain P. ; Poiré, Xavier ; Lopez-Corral, Lucia ; Nikolousis, Manos ; Pelosini, Matteo ; Ciceri, Fabio ; Baron, Frederic ; Bazarbachi, Ali ; Corbacioglu, Selim ; Savani, Bipin N. ; Peric, Zinaida ; Nagler, Arnon ; Carreras, Enric ; Mohty, Mohamad


Allogeneic hematopoietic cell transplantation (alloHCT) is a complex, potentially fatal therapy featuring a myriad of complications. Triggering event(s) of such complications vary significantly, but often a so-called "multi-organ failure" (MOF) is reported as the leading cause of death. The identification of the exact trigger of MOF is critical towards early and disease-specific intervention to ...


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