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EVALUATING PREDICTION METHODS FOR GLOMERULAR FILTRATION TO OPTIMISE DRUG DOSES IN OBESE AND NON‐OBESE PATIENTS

Busse, David ; Borghardt, Jens Markus ; Petroff, David ; Pevzner, Alice ; Dorn, Christoph ; El‐Najjar, Nahed ; Huisinga, Wilhelm ; Wrigge, Hermann ; Simon, Philipp ; Kloft, Charlotte



Abstract

The most suitable method for predicting the glomerular filtration rate (GFR) in obesity is currently debated. Therefore, multiple GFR/creatinine clearance prediction methods were applied to (morbidly) obese and non-obese patients ranging from moderate renal impairment to glomerular hyperfiltration and their predictions were rated based on observed fosfomycin pharmacokinetics, as model drug being ...

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