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Clinical management of patients receiving cell-based immunoregulatory therapy

Hutchinson, James A. ; Ahrens, Norbert ; Riquelme, Paloma ; Walter, Lisa ; Gruber, Michael ; Böger, Carsten A. ; Farkas, Stefan ; Scherer, Markus N. ; Broichhausen, Christiane ; Bein, Thomas ; Schlitt, Hans-J. ; Fändrich, Fred ; Banas, Bernhard ; Geissler, Edward K.



Abstract

Administering immunoregulatory cells as medicinal agents is a revolutionary approach to the treatment of immunologically mediated diseases. Isolating, propagating, and modifying cells before applying them to patients allows complementation of specific cellular functions, which opens astonishing new possibilities for gain-of-function antigen-specific treatments in autoimmunity, chronic ...

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