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Co-Stimulation of Oxytocin and Arginine-Vasopressin Receptors Affect Hypothalamic Neurospheroid Size

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Salehi, Mohammad Saied ; Neumann, Inga D. ; Jurek, Benjamin ; Pandamooz, Sareh
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 11 Jan 2022 15:05


Oxytocin (OXT) is a neuropeptide involved in a plethora of behavioral and physiological processes. However, there is a prominent lack of 3D cell culture models that investigate the effects of OXT on a cellular/molecular level. In this study, we established a hypothalamic neuronal spheroid model to investigate the cellular response in a more realistic 3D setting. Our data indicate that the ...


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