Co-Stimulation of Oxytocin and Arginine-Vasopressin Receptors Affect Hypothalamic Neurospheroid Size

URN to cite this document:: urn:nbn:de:bvb:355-epub-513691
DOI to cite this document:: 10.5283/epub.51369

Salehi, Mohammad Saied

; Neumann, Inga D.

; Jurek, Benjamin

; Pandamooz, Sareh

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Date of publication of this fulltext: 11 Jan 2022 15:05

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Abstract

Oxytocin (OXT) is a neuropeptide involved in a plethora of behavioral and physiological processes. However, there is a prominent lack of 3D cell culture models that investigate the effects of OXT on a cellular/molecular level. In this study, we established a hypothalamic neuronal spheroid model to investigate the cellular response in a more realistic 3D setting. Our data indicate that the ...