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Belated diagnosis in three patients with rifampicin-induced immune haemolytic anaemia

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Ahrens, Norbert ; Genth, Ramona ; Salama, Abdulgabar
Date of publication of this fulltext: 18 Jan 2022 06:28


We report three patients who developed haemolysis following rifampicin treatment. Initially, autoimmune haemolytic anaemia (AIHA) of the warm type and/or an acute haemolytic transfusion reaction (AHTR) was suggested. The direct antiglobulin tests (DAT) were strongly positive for IgG and C3d, and tests for rifampicin-dependent antibodies were positive in all three cases, featuring C-specificity in ...


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