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Membrane damage as mechanism of photodynamic inactivation using Methylene blue and TMPyP in Escherichia coli and Staphylococcus aureus

URN to cite this document:
urn:nbn:de:bvb:355-epub-514872
DOI to cite this document:
10.5283/epub.51487
Muehler, Denise ; Brandl, Elena ; Hiller, Karl-Anton ; Cieplik, Fabian ; Maisch, Tim
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License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 25 Jan 2022 05:59


Abstract

The worldwide threat of antibiotic resistance requires alternative strategies to fight bacterial infections. A promising approach to support conventional antibiotic therapy is the antimicrobial photodynamic inactivation (aPDI). The aim of this work was to show further insights into the antimicrobial photodynamic principle using two photosensitizers (PS) of different chemical classes, Methylene ...

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