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Membrane damage as mechanism of photodynamic inactivation using Methylene blue and TMPyP in Escherichia coli and Staphylococcus aureus

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Muehler, Denise ; Brandl, Elena ; Hiller, Karl-Anton ; Cieplik, Fabian ; Maisch, Tim
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 25 Jan 2022 05:59

This publication is part of the DEAL contract with Springer.


The worldwide threat of antibiotic resistance requires alternative strategies to fight bacterial infections. A promising approach to support conventional antibiotic therapy is the antimicrobial photodynamic inactivation (aPDI). The aim of this work was to show further insights into the antimicrobial photodynamic principle using two photosensitizers (PS) of different chemical classes, Methylene ...


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