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Increased Levels of sCD30 Have No Impact on the Incidence of Early ABMR and Long-Term Outcome in Intermediate-Risk Renal Transplant Patients With Preformed DSA

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Drasch, Thomas ; Bach, Christian ; Luber, Markus ; Spriewald, Bernd ; Utpatel, Kirsten ; Büttner-Herold, Maike ; Banas, Bernhard ; Zecher, Daniel
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 27 Jan 2022 15:15


Background: It is still incompletely understood why some patients with preformed donor-specific anti-HLA antibodies (DSA) have reduced kidney allograft survival secondary to antibody-mediated rejection (ABMR), whereas many DSA-positive patients have favorable long-term outcomes. Elevated levels of soluble CD30 (sCD30) have emerged as a promising biomarker indicating deleterious T-cell help in ...


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