Airway Delivery of Hydrogel-Encapsulated Niclosamide for the Treatment of Inflammatory Airway Disease

URN to cite this document:: urn:nbn:de:bvb:355-epub-518224
DOI to cite this document:: 10.5283/epub.51822

Ousingsawat, Jiraporn

; Centeio, Raquel ; Cabrita, Inês

; Talbi, Khaoula ; Zimmer, Oliver

; Graf, Moritz ; Göpferich, Achim

; Schreiber, Rainer

; Kunzelmann, Karl

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Date of publication of this fulltext: 28 Mar 2022 14:44

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Abstract

Repurposing of the anthelminthic drug niclosamide was proposed as an effective treatment for inflammatory airway diseases such as asthma, cystic fibrosis, and chronic obstructive pulmonary disease. Niclosamide may also be effective for the treatment of viral respiratory infections, such as SARS-CoV-2, respiratory syncytial virus, and influenza. While systemic application of niclosamide may lead ...