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Airway Delivery of Hydrogel-Encapsulated Niclosamide for the Treatment of Inflammatory Airway Disease

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Ousingsawat, Jiraporn ; Centeio, Raquel ; Cabrita, Inês ; Talbi, Khaoula ; Zimmer, Oliver ; Graf, Moritz ; Göpferich, Achim ; Schreiber, Rainer ; Kunzelmann, Karl
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 28 Mar 2022 14:44


Repurposing of the anthelminthic drug niclosamide was proposed as an effective treatment for inflammatory airway diseases such as asthma, cystic fibrosis, and chronic obstructive pulmonary disease. Niclosamide may also be effective for the treatment of viral respiratory infections, such as SARS-CoV-2, respiratory syncytial virus, and influenza. While systemic application of niclosamide may lead ...


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