The Drosophila functional Smad suppressing element fuss, a homologue of the human Skor genes, retains pro-oncogenic properties of the Ski/Sno family

URN to cite this document:: urn:nbn:de:bvb:355-epub-519252
DOI to cite this document:: 10.5283/epub.51925

Rass, Mathias

; Gizler, Laura

; Bayersdorfer, Florian ; Irlbeck, Christoph

; Schramm, Matthias Josef

; Schneuwly, Stephan

Preview

License: Creative Commons Attribution 4.0
PDF - Published Version
(5MB)

Date of publication of this fulltext: 14 Mar 2022 16:50

Alternative links to fulltext:DOI Publisher Publisher

Details

Preview

Indexed in

Export bibliographical data

Abstract

Over the years Ski and Sno have been found to be involved in cancer progression e.g. in oesophageal squamous cell carcinoma, melanoma, oestrogen receptor-positive breast carcinoma, colorectal carcinoma, and leukaemia. Often, their prooncogenic features have been linked to their ability of inhibiting the anti-proliferative action of TGF-beta signalling. Recently, not only pro-oncogenic but also ...