Efficacy of Vancomycin and Meropenem in Central Nervous System Infections in Children and Adults: Current Update

URN to cite this document:: urn:nbn:de:bvb:355-epub-520365
DOI to cite this document:: 10.5283/epub.52036

Schneider, Franziska ; Gessner, André

; El-Najjar, Nahed

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Date of publication of this fulltext: 05 Apr 2022 04:51

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Abstract

The current antimicrobial therapy of bacterial infections of the central nervous system (CNS) in adults and pediatric patients is faced with many pitfalls as the drugs have to reach necessary levels in serum and cross the blood-brain barrier. Furthermore, several studies report that different factors such as the structure of the antimicrobial agent, the severity of disease, or the degree of ...