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Snapshots of RNA polymerase III in action – A mini review

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Wang, Qianmin ; Daiß, Julia L. ; Xu, Youwei ; Engel, Christoph
Date of publication of this fulltext: 07 Apr 2022 04:44


RNA polymerase (Pol) III is responsible for the transcription of tRNAs, 5S rRNA, U6 snRNA, and other non-coding RNAs. Transcription factors such as TFIIIA, -B, -C, SNAPc, and Maf1 are required for promoter recognition, promoter opening, and Pol III activity regulation. Recent developments in cryo-electron microscopy and advanced purification approaches for endogenous multi-subunit complexes ...


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