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Current clinical practice and outcome of neoadjuvant chemotherapy for early breast cancer: analysis of individual data from 94,638 patients treated in 55 breast cancer centers

URN to cite this document:
urn:nbn:de:bvb:355-epub-521265
DOI to cite this document:
10.5283/epub.52126
Ortmann, Olaf ; Blohmer, J.-U. ; Sibert, N. T. ; Brucker, S. ; Janni, W. ; Wöckel, A. ; Scharl, A. ; Dieng, S. ; Ferencz, J. ; Inwald, E. C. ; Wesselmann, S. ; Kowalski, C. ; Denisjuk, E. ; Csorba, R. ; Rezek, D. ; Peschel, S. ; Denschlag, D. ; Schad, F. ; Dieterle, D. ; Lex, B. ; Rieger, L. ; Flock, F. ; Cramer, A. ; Strittmatter, H.-J. ; Bettscheider, J. ; Lindner, C. ; Stefek, A. ; Pauker, W. ; Hönig, A. ; Schrauder, M. ; Seeger, D. ; Kleine-Tebbe, A. ; Bleimehl, A. ; Groh, U. ; Gebauer, G. ; Vollert, H.-W. ; Zorr, A. ; Friedmann, W. ; Krabisch, P. ; Fritz, S. ; Schwämmle, A. ; Lucke, W. ; Schmatloch, S. ; Heyl, W. ; Deuschle, P. ; Arfsten, M. ; Scheler, P. ; Bleimehl, A. ; Ruf-Dördelmann, A. ; Brückner, B. ; Bauer, L. ; Koch, M. ; Monner, J. ; Nixdorf, A. ; Merte, A. ; Beldermann, F. ; Blohmer, J.-U. ; Janni, W. ; Felberbaum, R. ; De Wilde, R. L. ; Bolkenius, P. ; Lebrecht, A. ; Solomayer, E.-F. ; Hartmann, S. ; Hartkopf, A.
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Date of publication of this fulltext: 12 Apr 2022 04:59


Abstract

Neoadjuvant chemotherapy (NACT) is frequently used in patients with early breast cancer. Randomized controlled trials have demonstrated similar survival after NACT or adjuvant chemotherapy (ACT). However, certain subtypes may benefit more when NACT contains regimes leading to high rates of pathologic complete response (pCR) rates. In this study we analyzed data using the OncoBox research from ...

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