Advanced Immune Cell Profiling by Multiparameter Flow Cytometry in Humanized Patient-Derived Tumor Mice

URN to cite this document:: urn:nbn:de:bvb:355-epub-523011
DOI to cite this document:: 10.5283/epub.52301

Bruss, Christina ; Kellner, Kerstin ; Ortmann, Olaf

; Seitz, Stephan ; Brockhoff, Gero

; Hutchinson, James A.

; Wege, Anja Kathrin

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Date of publication of this fulltext: 25 May 2022 11:45

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Abstract

Simple Summary Immunotherapies have revolutionized the field of oncology and have been approved to treat cancer. Despite progress in immunotherapy, many challenges remain, including the identification (i) of predictive markers for treatment response or (ii) of beneficial T cell subsets involved in tumor elimination. "Humanized" mice are a promising translational model for studying the human ...