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Multiplex gene analysis reveals T-cell and antibody-mediated rejection-specific upregulation of complement in renal transplants

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Vonbrunn, Eva ; Ries, Tajana ; Söllner, Stefan ; Müller-Deile, Janina ; Büttner-Herold, Maike ; Amann, Kerstin ; Daniel, Christoph
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 24 May 2022 13:08


In renal transplantation, complement is involved in ischemia reperfusion injury, graft rejection and dysfunction. However, it is still unclear how induction of complement and its activation are initiated. Using allograft biopsies of a well-characterized cohort of 28 renal transplant patients with no rejection (Ctrl), delayed graft function (DGF), acute T-cell-mediated (TCMR) or antibody-mediated ...


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