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Transforming growth factor beta receptor II (TGFBR2) promoter region polymorphisms may be involved in mandibular retrognathism

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Kirschneck, Margarita ; Zbidat, Nermien ; Paddenberg, Eva ; Reis, Caio Luiz Bitencourt ; Madalena, Isabela Ribeiro ; Oliveira, Maria Angélica ; Lepri, César ; Proff, Peter ; Kirschneck, Christian ; Calvano Küchler, Erika
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Date of publication of this fulltext: 07 Jun 2022 12:39


Skeletal malocclusions are common phenotypes in humans and have a strong influence on genetic factors. Transforming growth factor beta (TGF beta) controls numerous functions of the human body, including cell proliferation, differentiation, and migration. Thus, this study is aimed at evaluating whether genetic polymorphisms in TGFB1 and its receptor TGFBR2 are associated with mandibular ...


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