Transforming growth factor beta receptor II (TGFBR2) promoter region polymorphisms may be involved in mandibular retrognathism

URN to cite this document:: urn:nbn:de:bvb:355-epub-523545
DOI to cite this document:: 10.5283/epub.52354

Kirschneck, Margarita ; Zbidat, Nermien

; Paddenberg, Eva

; Reis, Caio Luiz Bitencourt

; Madalena, Isabela Ribeiro

; Oliveira, Maria Angélica

; Lepri, César

; Proff, Peter

; Kirschneck, Christian

; Calvano Küchler, Erika

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 07 Jun 2022 12:39

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Abstract

Skeletal malocclusions are common phenotypes in humans and have a strong influence on genetic factors. Transforming growth factor beta (TGFβ) controls numerous functions of the human body, including cell proliferation, differentiation, and migration. Thus, this study is aimed at evaluating whether genetic polymorphisms in TGFB1 and its receptor TGFBR2 are associated with mandibular retrognathism ...