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PCSK9 and Cardiovascular Disease in Individuals with Moderately Decreased Kidney Function

Kheirkhah, Azin ; Lamina, Claudia ; Kollerits, Barbara ; Schachtl-Riess, Johanna F. ; Schultheiss, Ulla T. ; Forer, Lukas ; Sekula, Peggy ; Kotsis, Fruzsina ; Eckardt, Kai-Uwe ; Kronenberg, Florian


Background and objectives: Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a key regulator of lipid homeostasis. Studies investigating the association between PCSK9 and cardiovascular disease in large cohorts of patients with CKD are limited. Design, setting, participants, & measurements: The association of PCSK9 concentrations with prevalent and incident cardiovascular disease was ...


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