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RNA-Polymerase I: einer spezialisierten Transkriptionsmaschine auf der Spur

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Pilsl, Michael ; Tschochner, Herbert ; Griesenbeck, Joachim ; Engel, Christoph
[img]License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 06 Sep 2022 04:22

This publication is part of the DEAL contract with Springer.


In eukaryotes three major nuclear RNA Polymerases (Pols I, II and III) transcribe the genome. Pols II and III transcribe many different genes. Pol I has only one target from which it synthesizes the precursor for 3 of 4 ribosomal (r)RNAs accounting for up to 60 percent of total cellular RNA. Dedication of Pol I and its specific transcription factors to transcribe a single gene underlines the ...


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