Direct Potential Modulation of Neurogenic Differentiation Markers by Granulocyte-Colony Stimulating Factor (G-CSF) in the Rodent Brain

URN to cite this document:: urn:nbn:de:bvb:355-epub-529176
DOI to cite this document:: 10.5283/epub.52917

Kozole, Judith ; Heydn, Rosmarie ; Wirkert, Eva ; Küspert, Sabrina ; Aigner, Ludwig

; Bruun, Tim-Henrik

; Bogdahn, Ulrich

; Peters, Sebastian

; Johannesen, Siw

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 26 Sep 2022 05:05

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Abstract

The hematopoietic granulocyte-colony stimulating growth factor (G-CSF, filgrastim) is an approved drug in hematology and oncology. Filgrastim's potential in neurodegenerative disorders is gaining increasingly more attention, as preclinical and early clinical studies suggest it could be a promising treatment option. G-CSF has had a tremendous record as a safe drug for more than three decades; ...