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Peripheral Nerve Regeneration–Adipose-Tissue-Derived Stem Cells Differentiated by a Three-Step Protocol Promote Neurite Elongation via NGF Secretion

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Klein, Silvan ; Siegmund, Andreas ; Eigenberger, Andreas ; Hartmann, Valerie ; Langewost, Felix ; Hammer, Nicolas ; Anker, Alexandra ; Klein, Konstantin ; Morsczeck, Christian ; Prantl, Lukas ; Felthaus, Oliver
[img]License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 28 Sep 2022 14:18


The lack of supportive Schwann cells in segmental nerve lesions seems to be one cornerstone for the problem of insufficient nerve regeneration. Lately, adipose-tissue-derived stem cells (ASCs) differentiated towards SC (Schwann cell)-like cells seem to fulfill some of the needs for ameliorated nerve recovery. In this study, three differentiation protocols were investigated for their ability to ...


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