Peripheral Nerve Regeneration–Adipose-Tissue-Derived Stem Cells Differentiated by a Three-Step Protocol Promote Neurite Elongation via NGF Secretion

URN to cite this document:: urn:nbn:de:bvb:355-epub-529404
DOI to cite this document:: 10.5283/epub.52940

Klein, Silvan

; Siegmund, Andreas ; Eigenberger, Andreas

; Hartmann, Valerie ; Langewost, Felix ; Hammer, Nicolas ; Anker, Alexandra ; Klein, Konstantin

; Morsczeck, Christian ; Prantl, Lukas

; Felthaus, Oliver

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 28 Sep 2022 14:18

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Abstract

The lack of supportive Schwann cells in segmental nerve lesions seems to be one cornerstone for the problem of insufficient nerve regeneration. Lately, adipose-tissue-derived stem cells (ASCs) differentiated towards SC (Schwann cell)-like cells seem to fulfill some of the needs for ameliorated nerve recovery. In this study, three differentiation protocols were investigated for their ability to ...