Benchmarking One-Phase Lipid Extractions for Plasma Lipidomics

URN to cite this document:: urn:nbn:de:bvb:355-epub-530384
DOI to cite this document:: 10.5283/epub.53038

Höring, Marcus

; Stieglmeier, Christoph

; Schnabel, Katja ; Hallmark, Tucker ; Ekroos, Kim ; Burkhardt, Ralph

; Liebisch, Gerhard

License: Creative Commons Attribution Non-commercial No Derivatives 4.0
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Date of publication of this fulltext: 24 Oct 2022 05:34

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Abstract

A key element of successful lipidomics analysis is a sufficient extraction of lipid molecules typically by two-phase systems such as chloroform-based Bligh and Dyer (B&D). However, numerous metabolomics and lipidomics studies today apply easy to use one-phase extractions. In this work, quantitative flow injection analysis high-resolution mass spectrometry was applied to benchmark the lipid ...