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Benchmarking One-Phase Lipid Extractions for Plasma Lipidomics

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Höring, Marcus ; Stieglmeier, Christoph ; Schnabel, Katja ; Hallmark, Tucker ; Ekroos, Kim ; Burkhardt, Ralph ; Liebisch, Gerhard
Date of publication of this fulltext: 24 Oct 2022 05:34


A key element of successful lipidomics analysis is a sufficient extraction of lipid molecules typically by two-phase systems such as chloroform-based Bligh and Dyer (B&D). However, numerous metabolomics and lipidomics studies today apply easy to use one-phase extractions. In this work, quantitative flow injection analysis high-resolution mass spectrometry was applied to benchmark the lipid ...


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