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Paralytic Impact of Centrifugation on Human Neutrophils

URN to cite this document:
urn:nbn:de:bvb:355-epub-532146
DOI to cite this document:
10.5283/epub.53214
Hundhammer, Tobias ; Gruber, Michael A. ; Wittmann, Sigrid
[img]License: Creative Commons Attribution 4.0
PDF - Published Version
(4MB)
Date of publication of this fulltext: 17 Nov 2022 12:54



Abstract

Centrifugation is a common step in most of the popular protocols for the isolation of neutrophils from whole blood. Inconsistent results from previous studies on neutrophils may originate from an underestimation of the centrifugation effect, as in consequence impaired, not native cells, being investigated. We hypothesize, that centrifugation significantly impairs major neutrophil functions. ...

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